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KMID : 1001920210640050726
Journal of Korean Neurosurgical Society
2021 Volume.64 No. 5 p.726 ~ p.731
Source Image Based New 3D Rotational Angiography for Differential Diagnosis between the Infundibulum and an Internal Carotid Artery Aneurysm : Pilot Study
Jang Hyeon-Gyu

Jung Woo-Sang
Myoung Seong-Uk
Kim Jung-Jae
Jang Chang-Ki
Cho Kwang-Chun
Abstract
Objective: Distinguishing between an infundibulum and a true aneurysm is clinically important. This study aimed to evaluate whether using source image based new three-dimensional rotational angiography (S-n3DRA) can increase the rate of aneurysm detection and improve distinction between a true aneurysm and an infundibulum.

Methods: Twenty-two consecutive patients with 23 lesions, were evaluated by time-of-flight (TOF) magnetic resonance angiography (MRA), S-n3DRA, and digital subtraction angiography (DSA). The data were retrospectively and independently reviewed by two neurointerventionists, and the diagnoses based on TOF MRA, S-n3DRA, and DSA were compared. The diagnostic efficacy (interobserver agreement and diagnostic performance) of S-n3DRA was compared with that of TOF MRA.

Results: S-n3DRA showed higher interobserver agreement (¥ê=0.923) than TOF MRA (¥ê=0.465) and significantly higher accuracy than MRA in distinguishing an aneurysm from an infundibulum (p=0.0039).

Conclusion: Compared to MRA, S-n3DRA could provide better screening accuracy and information for distinguishing an aneurysm from an infundibulum. Therefore, S-n3DRA has the potential to reduce the need for DSA.
KEYWORD
Source image based new three-dimensional rotational angiogram, Time-of-flight magnetic resonance angiography, Digital subtraction angiography, Intracranial aneurysm, Infundibulum
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